Welcome to The Lockery Lab
We study how the nervous system controls behavior by analyzing the simple neural networks that control spatial orientation behaviors and decision making, in the nematode worm Caenorhabditis elegans. C. elegans has a small nervous system (302 neurons), whose neurons and connectivity pattern have been completely characterized. Together with an entirely sequenced genome and high accessibility to genetic analysis, this organism provides an unique opportunity to study the neural and genetic basis of behavior. Our research integrates a wide range of levels of analysis and experimental approaches, including quantitative analysis of behavior, neuronal ablation, computer modeling, electrophysiology, calcium imaging, optogenetics and microfluidics.